Senior / Principal Associate Scientist, In vivo immunology
Full Time • Cambridge
Benefits:
- 401(k)
- Bonus based on performance
- Competitive salary
- Dental insurance
- Health insurance
- Paid time off
- Parental leave
- Stock options plan
- Vision insurance
We are seeking a motivated biologist with expertise in developing and executing in vivo models of autoimmune and inflammatory disease in support of biologics drug development. As a Senior Associate/Principal Associate Scientist, you will be involved in Zag’s immunology research efforts in support of advancement of the company’s novel therapeutics platform for autoimmune disease. The successful candidate has a bias-to-action, thrives in a collaborative work environment, and is motivated by the desire to improve treatment options for patients with chronic disease.
RESPONSIBILITIES:
- Support development of preclinical models of inflammation and perform mechanistic studies to demonstrate activity and mechanisms of action (MoA) of our novel biologic agents
- Design and execute well-controlled experiments, independently perform data analysis and summarize findings to key stakeholders
- Analyze data and present scientific findings at internal research meetings
- Document research activities and findings in electronic laboratory notebook and reagent registries in keeping with the highest industry standards
REQUIREMENTS:
- The leveling of this position will be commensurate with experience.
- Senior Associate Scientist candidates require a BA/BS or equivalent with 4+ years or MS degree with 2+ years of relevant industry or academic research experience
- Principal Associate Scientist candidates require a BA/BS or equivalent with 7+ years or MS degree with 5+ years of relevant industry or academic research experience
- Significant hands-on experience with in vivo procedures using mice, including injections (IV, SC, IP), blood/tissue collection, etc.
- Experience with standard immunology assays, including isolation of immune cells from tissues, multiparameter flow cytometry, multiplex cytokine analysis and qPCR
- Proficiency in scientific computer programs including Microsoft Excel, GraphPad Prism, and FlowJo
- Excellent organization and troubleshooting skills
- Excellent communication and interpersonal skills, and the ability to thrive in a dynamic cross-functional environment
- Experience with developing and optimizing immuno-assays (e.g., ELISA, MSD, Luminex, etc.) is desirable
Zag Bio values the diversity of our workforce and maintains a deeply respectful, values-driven working environment. We are committed to equal employment opportunities and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation, or any characteristic protected under applicable law.
We are not accepting unsolicited resumes from employment agencies for any employment opportunities at this time.
Zag Bio was founded with a vision to develop more precise, potent, and impactful medicines for immune-mediated diseases. Zag Bio is working to discover and develop therapies targeted directly to the thymus, with the goal of generating central immune tolerance.
Our technology platform is inspired by the work of co-founder Diane Mathis of Harvard Medical School, and operates across multiple therapeutic platforms, underpinned by a deep technical interrogation of thymus biology. In addition to Dr. Mathis, Zag Bio was co-founded by Alan Crane (Polaris Partners), Jo Viney (Seismic Therapeutics), and John Kulman (Zag Bio). Zag Bio is a stealth mode biotech company, poised for growth in line with our ambition to transform the treatment of immune-mediated diseases.
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